Diagnosed with Gleason 10 cancer (one core of 12 positive) in 2015. Opted for surgery at MD Anderson in Houston, TX, due to the aggressive nature of the cancer. Post op the Gleason score was reduced to 9 (4+5). Received an excellent pathology report after surgery, cancer was contained in the capsule. No additional treatment beyond surgery was necessary, based on the pathology.
Six month PSA was "undetectable". One year PSA still "undetectable". Eighteen month PSA remained "undetectable". That was all the great news. In July of this year, my two year PSA check came back at 0.1. MD Anderson wants me back in 4 months for another PSA check. Due to the aggressive Gleason 9 cancer, I of course am a bit panicked by the 0.1 reading. We recently relocated to California. Had a different lab pull a PSA out here last week and it was 0.12. Obviously more nervous now, as that is an escalation in one month.
OK...I know it was from a different lab, and obviously it was a more sensitive test. Here is the question for the very experienced group that follows this website. Is it time for panic, or do I stay calm until my next PSA at the end of Novemeber in Texas? As most of you will no doubt know - staying calm and not worrying is a bit of a challenge with this dreaded disease. Any input form the forum would be appreciated. [Although it is difficult to refrain from worrying, a few more data points would give a much better indication of what is happening. Changing from one lab to another can certainly introduce a level of variability that can give a false indication of progression of the disease. For some labs, 0.1 is the smallest value that can be measured.] Either way, I will post updates as I progress - as others - especially those with high Gleason scores, may find the information useful.
Baron's e-mail address is: bfigel AT scsfence.com (replace "AT" with "@")